Rabeprazole Tablet IP

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  • Mechanism of Action: Rabeprazole deactivates the H+/K+-ATPase enzyme, also known as the "proton pump," in the lining of the stomach walls, thereby blocking the final step of acid secretion.
  • Uses: It is primarily used to treat acid-related conditions of the stomach and esophagus, including:
    • Gastroesophageal reflux disease (GERD) and its symptoms like heartburn and acid reflux.
    • Healing and maintenance of gastric and duodenal ulcers.
    • Zollinger-Ellison syndrome, a rare condition involving excessive stomach acid production.
    • Eradication of Helicobacter pylori (H. pylori) bacteria (in combination with antibiotics like amoxicillin and clarithromycin).
  • Administration: Tablets should be swallowed whole; they should not be chewed, crushed, or split. It is usually taken once daily, preferably in the morning before a meal. 

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